Adefovir Dipivoxil For The Treatment Of Chinese Compensated Chronic Hepatitis B(CHB)Patients
Status:
Completed
Trial end date:
2008-09-01
Target enrollment:
Participant gender:
Summary
This 48-week open-label study of local manufactured adefovir dipivoxil Tablet evaluates the
efficacy and safety of adefovir 10mg once daily in Chinese subjects with compensated CHB.
Primary endpoint is proportion of subjects achieving HBV DNA undetectable (<=1000 copies/mL
by by Roche COBAS AMPLICOR HBV MONITOR Test) at week 48. Approximately 1250 patients will be
recruited in 30 study centers in China. The subjects are offered 48 weeks of open label
adefovir dipivoxil treatment, with assessments every three months, after with is a 12-week
post study treatment follow-up prior to study completion.