Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Post-operative Pain Relief and Decrease Opioid Consumption: a Prospective Randomized Controlled Trial

• Status: Completed
• Trial end date: 2021-05-29
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether the addition of magnesium to bupivacaine for the post-operative adductor canal blocks (ACB) can decrease opioid consumption and improve pain management for patients after same-day discharge total knee arthroplasty (TKA).

The investigators will assess whether the addition of magnesium will decrease visual analog scale (VAS) pain scores, decrease post-operative total opioid consumption (oral morphine equivalents), decrease the incidence of post-operative nausea and vomiting (PONV), and improve patient satisfaction in comparison to when magnesium is not administered.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Wayne State University

Criteria

Inclusion Criteria:

• Patients undergoing unilateral primary total knee arthroplasty with spinal anesthetic and MAC followed by a unilateral adductor canal block with ultrasound guidance.

Exclusion Criteria:

• Patients on chronic anticoagulation upon admission

• Patients with significant genetic or acquired clotting/bleeding disorders (hemophilia, DIC, etc.) or significant platelet dysfunction

• Patients with prior back surgery or leg surgery that precludes spinal or regional anesthesia

• Infection at sites for regional/spinal anesthesia

• Allergy to local anesthetics