Additive Effect of Endonase on Eradication Rate of First Line Therapy for Helicobacter Pylori
Status:
Completed
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
Endonase, a kind of protease, is known to cause both extensive degradation of mucins and a
reduction in mucus viscosity. As part of the search for more effective forms of therapy
against H. pylori when it colonizes not only the surface of the surface mucosal cells but
also the surface mucous gel layer covering the mucosal surface of the stomach. The
investigators decided to investigate whether or not endonase might have additive effect of
pronase on the efficacy of eradication therapy against Helicobacter pylori.