Overview

Adding Venetoclax to the High-dose Chemotherapy Regimen Prior to Mismatche Allogeneic Stem Cell Transplant

Status:
WITHDRAWN
Trial end date:
2027-08-31
Target enrollment:
Participant gender:
Summary
Patients eligible for a mismatch allogeneic stem cell transplant will receive Venetoclax daily for 7 days prior to transplant in addition to the following chemotherapy regimen: Decitabine daily for 5 days, Fludarabine daily for 5 days, and Busulfan daily for 2 days followed by 1 day of total body irradiation. Stem cell transplant will occur thereafter.
Phase:
PHASE2
Details
Lead Sponsor:
Northside Hospital, Inc.
Treatments:
Busulfan
Decitabine
fludarabine
venetoclax
Whole-Body Irradiation