Adding Magnesium Sulfate to Bupivacaine for Ilioinguinal and Iliohypogastric Nerve Block
Status:
Completed
Trial end date:
2020-04-21
Target enrollment:
Participant gender:
Summary
Regional block of ilioinguinal and iliohypogastric (IIIH) nerves has been applied to provide
postoperative analgesia after inguinal hernia repair. Magnesium sulfate (MgSo4) blocks
N-methyl-d-aspartate receptors, and that is why, it was used as an adjuvant to the local
anesthetic (LA) in different anesthetic approaches. Although the prolongation in
postoperative duration resulting from the addition of MgSO4 to LA was significant in some
literature studies, it was insignificant in others. This study was designed to investigate
the adjunctive effect of MgSo4 when added to bupivacaine for IIIH blockade on the
postoperative analgesic duration as a primary outcome and on the verbal rating scale (VRS)
scores, analgesic consumption, and hemodynamics as secondary outcomes.