Added Value of Systemic Lidocaine on Postoperative Pain, Opiate Use and Nausea After Knee Arthroscopy
Status:
Completed
Trial end date:
2019-06-30
Target enrollment:
Participant gender:
Summary
Local intra-articular injection of anesthetics (LIA) is increasingly used during knee
arthroscopy for pain relief. The LIA can only be performed at the end of surgery as the knee
joint is continuously flushed during the arthroscopy. As a consequence, an optimal analgesic
effect is only obtained one hour after surgery and opiates are typically used as pain relief
in the immediate postoperative period. Since these opiates have a number of side effects such
as nausea, vomiting and drowsiness, other analgetic methods are desirable.
Intravenous administration of lidocaine, a safe, inexpensive analgesic, is already used in
major (abdominal) surgeries and might also be a promising method for pain relief in the first
hour after knee arthroscopy, in anticipation of the onset of the analgesic effect of the LIA.
The aim of this study is to verify if systemic administration of lidocaine has a beneficial
effect on the pain immediately after knee arthroscopy. In addition, the effect of systemic
lidocaine administration on postoperative nausea, vomiting and general patient comfort will
be evaluated.