Adaptive Treatment for Alcohol and Cocaine Dependence
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
1. Primary objective #1: Determine the relative effectiveness of MI-IOP and MI-PC in the
full study sample with regard to treatment engagement over weeks 1-12 and
cocaine/alcohol use over weeks 1-24.
- Hypothesis 1: An intervention that explores several possible treatment options with
the patient and provides the chosen option (e.g., MI-PC) will produce higher rates
of treatment engagement than an intervention focused on engagement in IOP only
(e.g., MI-IOP).
- Hypothesis 2: An intervention that explores several possible treatment options with
the patient and provides the chosen option (e.g., MI-PC) will produce better
cocaine/alcohol use outcomes than an intervention focused on engagement in IOP only
(MI-IOP).
- Secondary analysis 1: Among the Non-engaged patients, determine rates of selection
of each of the three options in MI-PC, retention rates within each option, and
cocaine/alcohol use outcomes in each option.
- Secondary analysis 2: Among the Engaged patients, determine rates of selection of
each of the three options in MI-PC, retention rates within each option, and
cocaine/alcohol use outcomes in each option.
2. Primary objective #2: Determine whether the relative effectiveness of MI-IOP and MI-PC
varies as a function of engagement group, with regard to treatment engagement over weeks
1-12 and cocaine/alcohol use outcomes over weeks 1-24.
- Hypothesis 1: The predicted main effect on retention favoring MI-PC over MI-IOP
will be significantly larger among patients in the Non-engaged group than among
those in the Engaged group.
- Hypothesis 2: The predicted main effect on cocaine/alcohol use outcomes favoring
MI-PC over MI-IOP will be significantly larger among patients in the Non-engaged
group than among those in the Engaged group.