Overview

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

Status:
RECRUITING
Trial end date:
2028-08-01
Target enrollment:
Participant gender:
Summary
This is a single arm phase 2 trial is to evaluate the efficacy of SRS plus adagrasib for the treatment of brain metastases for patients with KRAS G12C-mutated non-small cell lung cancer (NSCLC). A total of 30 patients will be enrolled on this study.
Phase:
PHASE2
Details
Lead Sponsor:
Ryan Gentzler, MD
Collaborators:
Mirati Therapeutics Inc.
University of Virginia
Treatments:
adagrasib
Radiosurgery