Acute Renal Failure Post Liver Transplantation

• Status: Completed
• Trial end date: 2014-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Trial to test the effect of administering N-acetylcysteine on cytokines and markers of oxidant stress and the incidence of acute renal failure post liver tranplant

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Baylor Research Institute
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

• First liver transplant

• Normal renal function before transplantation [serum creatinine ≤ 1.5 mg / dl]

• No requirements for dialysis before transplantation

• Age greater than 18 years

Exclusion Criteria:

• Re-transplant

• Renal dysfunction i.e. serum creatinine > 1.5 mg/dl

• Need for dialysis before transplantation

• Presence of Hepatorenal or Hepatopulmonary syndrome*

• Combined liver and kidney transplant

• Peptic ulcer disease

• Pregnancy