Acute Normovolemic Hemodilution on ROTEM in Cardiac Surgery
Status:
Completed
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
Impact of acute normovolemic hemodilution (ANH) using hydroxyethyl starch before initiating
cardiopulmonary bypass (CPB) on whole blood viscoelastic profile after CPB has not been well
established.
Patients undergoing cardiac surgery employing moderate hypothermic CPB (n=40) are randomly
allocated into one of two groups: in Group-ANH(n=20), ANH is applied by using a balanced
hydroxyethyl starch (HES 130/0.6); and in Group-C, ANH is not applied.
After weaning from CPB, intergroup differences of INTEM, EXTEM, FIBTEM and APTEM profiles are
analyzed.
As a primary outcome, inter-group difference between maxiaml clot firmness of EXTEM will be
determined at 10 min after ANH in Group-ANH and that at control.