Acute Neuroimmune Effects of Alcohol Using Free Water Imaging

• Status: Completed
• Trial end date: 2017-09-28
• Target enrollment: 0
• Participant gender: All

Summary

This study examines the effects of moderate alcohol intake on the brain, the immune system, and cognition.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Brown University
• Collaborator: National Institute of General Medical Sciences (NIGMS)
• Treatments: Ethanol

Criteria

Inclusion Criteria:

• Ages 21-45 years

• Able to speak and read English at least at 8th grade level

• Moderate self-reported alcohol use in the past year

• Body mass index in normal to overweight range

• Right-handed

Exclusion Criteria:

• History of heavy drinking

• Currently seeking alcohol or drug treatment

• Chronic disease requiring use of medication

• Recent antibiotic or probiotic use

• Chronic daily use of NSAIDs

• Chronic GI disorder

• Use of illicit drugs

• Major psychiatric disorder or suicidality

• Fainting, weakness, infection, excessive bruising, or distress resulting from standard blood draw

• Safety contraindication for MRI scan

• Inability to abstain from use of tobacco products prior to or during study

• Inability to abstain from use of cannabis prior to or during study

• Pregnant, nursing, or may become pregnant