Acute Impact of Intramuscular (IM) Aripiprazole and Olanzapine on Insulin Resistance in High Risk Prediabetics
Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
Antipsychotic medicines used to treat mental illnesses have been associated with effects on
blood sugar control. Laboratory studies have shown that certain medications in particular may
alter how insulin works. One purpose of this study is determine if antipsychotic medications
have immediate effects on insulin action in individuals who do not have a mental disorder,
but who have risk factors for diabetes. A second purpose is to demonstrate the feasibility of
using volunteers without psychiatric disorders, and who do not take psychiatric medications,
as a means for studying antipsychotic metabolic effects.