Acute Effects of Sildenafil on Endothelial Function in People With Diabetes
Status:
Completed
Trial end date:
2003-06-01
Target enrollment:
Participant gender:
Summary
This is a double-blind, placebo-controlled, cross-over trial using a single dose of 100 mg
sildenafil or placebo in 40 subjects with T2DM without known cardiovascular disease. Effects
on haemodynamic parameters, flow mediated dilatation (FMD) in brachial artery, cardiovascular
autonomic function tests, and spontaneous baroreflex sensitivity (BRS) were investigated.