Acupuncture Combined With Mirabegron in the Treatment of OAB
Status:
Active, not recruiting
Trial end date:
2024-12-31
Target enrollment:
Participant gender:
Summary
Introduction: As conventional treatments for overactive bladder (OAB) have not yet shown
satisfactory results, new approaches are needed. Therefore, this study aimed to investigate
the efficacy and safety of acupuncture combined with mirabegron for the treatment of OAB.
Methods: This prospective cohort study enrolled 80 OAB patients who were then divided into
control and treatment groups using a randomized number-table method. The control group was
administered mirabegron alone (50 mg/day), while the treatment group was administered
mirabegron orally along with acupuncture at the following points: guanyuan (CV4), zhongji
(CV3), and sanyinjiao (SP6). The OAB symptom score (overactive bladder syndrome score
[OABSS]), voiding, urgency, nocturia, incontinence, and incidence of related adverse events
were compared between the two groups at baseline and after 4, 8, and 12 weeks of treatment.
Phase:
Phase 1
Details
Lead Sponsor:
The Affiliated Ganzhou Hospital of Nanchang University