Active Comparator-Controlled Study to Assess Safety and Efficacy of ISIS-FXIRx in Total Knee Arthroplasty
Status:
Completed
Trial end date:
2014-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is:
- To assess the safety and efficacy profile of ISIS-FXIRx, including incidence of bleeding
and VTE, in patients undergoing total knee arthroplasty.
- To compare the efficacy and safety profile of ISIS-FXIRx in patients who achieve less
than or equal to 0.2 U/mL FXI activity levels to that of enoxaparin.