Overview

Acthar in Treatment of Refractory Dermatomyositis and Polymyositis

Status:
Completed
Trial end date:
2016-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to evaluate the effectiveness of the study drug, ACTH Gel in people diagnosed with dermatomyositis a disease that causes muscle weakness and is associated with a rash (DM) or polymyositis (PM) a disease that causes muscle weakness without a rash. The study doctors want to evaluate whether ACTH Gel will improve the symptoms of this disease. This drug is approved by the Food and Drug Administration (FDA) for dermatomyositis (DM) and polymyositis (PM). ACTH gel has been an FDA-approved treatment for myositis since 1952, and in 2010 the FDA retained PM and DM as diseases approved for ACTH gel use.
Phase:
Phase 2
Details
Lead Sponsor:
Rohit Aggarwal, MD
University of Pittsburgh
Collaborator:
Mallinckrodt
Treatments:
Adrenocorticotropic Hormone
beta-Endorphin
Hormones
Melanocyte-Stimulating Hormones