Overview

Acid Tranexamic Effectiveness in Reducing the Intraoperative Bleeding in Palatoplasty

Status:
Completed
Trial end date:
2015-03-01
Target enrollment:
0
Participant gender:
All
Summary
Randomized study evaluating the role of tranexamic acid in reducing intraoperative bleeding in palatoplasty.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Professor Fernando Figueira Integral Medicine Institute
Treatments:
Tranexamic Acid
Criteria
Inclusion Criteria:

- Palatoplasty indication in patients of any age with presence of congenital cleft
palate (with or without associated cleft lip), in the study hospital

Exclusion Criteria:

- Preoperative hemoglobin lower than 10 mg / dl or platelet count less than 100,000 /
mm3 ;

- Presence of coagulopathy caused by known coagulation cascade disorders or systemic
diseases, or excessive bleeding history on previous occasions;

- History of bleeding disorders in first-degree relatives;

- Use of medications that may interfere with the coagulation cascade (platelet
inhibitors or anticoagulants);

- Indication of secondary palatoplasty with the purpose of correction oro-nasal fistula;

- Known allergy to tranexamic acid.