Acetylcysteine, Theophylline, and a Combination of Both in the Prophylaxis of Contrast-Induced Nephropathy
Status:
Completed
Trial end date:
2004-10-01
Target enrollment:
Participant gender:
Summary
Several studies demonstrated a significant reduction of contrast-induced nephropathy (CIN;
definition: increase in serum creatinine of >=0.5mg/dl and/or >=25% increase within 48h after
contrast-medium) by acetylcysteine (A) or theophylline (T). However, the results are
contradictory. Therefore, it was the aim of our double-blind study to compare the effects of
A, T, a combination of A and T (A+T), and placebo (P).