Acetyl-L-Carnitine Reduces Depression and Improves Quality of Life in Patients With Minimal Hepatic Encephalopathy
Status:
Completed
Trial end date:
2005-11-01
Target enrollment:
Participant gender:
Summary
Minimal hepatic encephalopathy represents a common complication present in well-compensated
cirrhotic patients that impairs patients daily functioning and health-related quality of
life. Acetyl-L-carnitine has been shown to be useful in improving blood ammonia and cognitive
functions in cirrhotic patients with minimal hepatic encephalopathy. This study evaluated the
effects of acetyl-L-carnitine treatment on health related quality of life and on depression
in patients with minimal hepatic encephalopathy.