Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever

• Status: Withdrawn
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the efficacy of the an N-acetyl-p-aminophenol (APAP, also known as acetaminophen) and N-acetylcysteine (NAC) combination versus an APAP-placebo combination as an anti-pyretic agent.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Columbia University
• Treatments: Acetaminophen; Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

• adults aged 18 to 75 years old

• admitted to an inpatient unit at Columbia-Presbyterian Medical Center

• fever defined as an oral temperature of 38.5°C

Exclusion Criteria:

• if oral temperature cannot be obtained

• abnormal aminotransferase levels

• prior adverse reaction to acetaminophen or N-acetylcysteine