Acetaminophen for Fetal Tachycardia: a Randomized Pilot Trial

• Status: Terminated
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The most common cause of fetal tachycardia is maternal fever. Fetal tachycardia often precedes the maternal fever, and fetal tachycardia confounds the interpretation of electronic fetal monitoring (EFM), increasing the rate of cesarean delivery for non-reassuring fetal status (NRFS). Our hypothesis is that treatment of fetal tachycardia with acetaminophen will significantly lower maternal body temperature and significantly lower baseline fetal heart rate (FHR). The importance is that interpretation of EFM will improve, thus allowing for a decrease in cesarean delivery for NRFS.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Weill Medical College of Cornell University
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

• Term pregnancy

• Singleton pregnancy

• Pregnancy with cephalic presentation

• Pregnancy in active phase labor

• Fetal tachycardia

Exclusion Criteria:

• Acetaminophen allergy

• Clinical chorioamnionitis

• Maternal fever

• Non-reassuring fetal status or fetal heart rate abnormalities requiring cesarean delivery

• Previous cesarean delivery

• Multifetal gestation

• Breech presentation

• Known fetal anomaly

• Known contraindication to vaginal delivery