Acetaminophen for Chronic Pain in Hysterectomy

• Status: Completed
• Trial end date: 2014-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

The investigators hypothesized that 1 mg of acetaminophen 4 times per day for 3 days prevent chronic pain in hysterectomy patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mustafa Kemal University
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

• Patients 18-80 years old scheduled for hysterectomy

• Horizontal or vertical abdominal skin incision

• Ability to operate a patient-controlled analgesia (PCA) device

• Written informed consent.

Exclusion Criteria:

• ASA Physical Status I-II, emergency or urgent procedure

• Pre-existing chronic pain (at any site) requiring opioid analgesia

• History of significant Axis I psychiatric disease (major depressive disorder, bipolar disorder, schizophrenia, etc.)

• Significant hepatic (ALT or AST > 2 times normal) or renal (serum creatinine > 2 mg/dl) impairment; allergy to acetaminophen

• Pregnancy