Accelerated Titration of Oxytocin for Nulliparous Patients With Labour Dystocia: ACTION Pilot Study
Status:
Terminated
Trial end date:
2013-11-01
Target enrollment:
Participant gender:
Summary
The ultimate objective is to test the hypothesis that an 'accelerated titration' protocol for
labour augmentation with oxytocin reduces the risk of caesarean births relative to a 'gradual
titration' protocol.
The aims of this pilot feasibility are:
1. To assess the feasibility of a large multi-centre randomized control trial comparing the
two above oxytocin protocols (accelerated titration versus gradual titration for
correction of dystocia).
2. More specifically, to identify potential challenges in the study implementation,
particularly with respect to patient recruitment, randomization, blinding, and
compliance/adherence to the labour management guidelines and study protocols.
3. To obtain preliminary data on the acceptability of the accelerated oxytocin titration
protocol among obstetrical providers and participants.
Phase:
Phase 3
Details
Lead Sponsor:
Ottawa Hospital Research Institute
Collaborators:
Canadian Institutes of Health Research (CIHR) Sainte Justine Hospital Research Institute The Ottawa Hospital The Physicians' Services Incorporated Foundation