Accelerated Corneal Cross-linking With Different Riboflavin Solutions

• Status: Completed
• Trial end date: 2020-03-30
• Target enrollment: 0
• Participant gender: All

Summary

Following the Bunsen-Roscoe law, accelerated cross-linking protocols with higher irradiation intensities and shorter irradiation times have been introduced. In addition, new riboflavin solutions with HPMC (hydroxylpropyl methylcellulose) instead of dextran found its way into CXL-treatment. The aim of this trial is to evaluate clinical outcomes in an accelerated corneal collagen cross-linking protocol with different riboflavin solutions.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Vienna
• Treatments: Dextrans; Riboflavin

Criteria

Inclusion Criteria:

• Progressive Keratoconus

• Indication for treatment

• Preoperative Pachymetry > 400

Exclusion Criteria:

• Pregnancy

• Re-CXL

• Keratitis

• Other visual acuity limiting eye diseases than corneal ectatic diseases