This study will examine whether pretreatment with two doses of acamprosate for seven days
prior to abstinence lessens the intensity of acute withdrawal from alcohol compared with a
placebo. Subjects will be randomly assigned to receive either one of two doses of acamprosate
or placebo for seven days. This will be followed by a four- day inpatient period when
withdrawal will be monitored. Additional drinking information will be obtained at a three
month followup interview.
Phase:
Phase 2
Details
Lead Sponsor:
Yale University
Collaborator:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)