Overview

Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid Users

Status:
Completed

Trial end date:
2011-05-01

Target enrollment:

Participant gender:

Summary

The primary purpose of this study is to determine the abuse potential of EMBEDA compared to controlled release morphine when crushed and taken orally by non-dependent recreational opioid users; secondary purposes include to determine the abuse potential of crushed EMBEDA relative to placebo and and to compare the pharmacokinetics and safety of crushed EMBEDA with crushed controlled-release morphine and crushed placebo.

Phase:

Phase 1

Details

Lead Sponsor:

Pfizer

Treatments:

Analgesics, Opioid
Morphine
Naltrexone