Overview

Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users

Status:
Completed
Trial end date:
1998-03-01
Target enrollment:
0
Participant gender:
All
Summary
Buprenorphine is a medication used to treat opioid addiction, but individuals who use this drug are at risk of abusing it. A buprenorphine and naloxone combination may reduce the likelihood of buprenorphine addiction. This study will evaluate the potential for abuse of buprenorphine and a buprenorphine and naloxone combination in non-dependent opioid users.
Phase:
N/A
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
National Institute on Drug Abuse (NIDA)
Treatments:
Buprenorphine
Hydromorphone
Naloxone
Criteria
Inclusion Criteria:

- Current opioid abuse

- Not physically dependent on opioids

Exclusion Criteria:

- Significant medical or psychiatric illness (e.g., insulin-dependent diabetes or
schizophrenia)

- Seeking substance abuse treatment (will be assisted with referrals to community-based
treatment programs)

- Pregnant