Overview

Absorption of Paracetamol, Talinolol and Amoxicillin After Oral Administration Using Non-caloric and Caloric Water

Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
To visualize the localization and to measure the volume of water in the small intestine by T2-weighted MRI imaging after oral administration of 240 ml water (non-caloric water) and after administration of 240 ml water containing 25.5 g sucrose (105 kcal, caloric water). To measure pharmacokinetics of the probe-drugs paracetamol, talinolol and amoxicillin after oral administration dissolved in 240 ml non-caloric and in 240 ml caloric water.
Phase:
Phase 1
Details
Lead Sponsor:
University Medicine Greifswald
Treatments:
Acetaminophen
Amoxicillin
Talinolol