Absorption and Pharmacokinetics of Nitroglycerin to a New Formulation

• Status: Unknown status
• Trial end date: 2020-12-23
• Target enrollment: 0
• Participant gender: All

Summary

The study evaluate the absorption rate of different sublingual formulation of nitroglycerine (NTG) either in the form of available tablets or a new rapid absorbable gelation capsule formulation "NTG1523" by determining T-max and area under the response curve of nitoglycerine in blood concentration as well as from clinical effects after intake. Data is entered on data sheet in anonymous form and processed. The results are presented in anonymous form by publication and lecture. Experts are given the supplement: "The applicant's rights in a biomedical research project

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Kolding Sygehus
• Treatments: Nitroglycerin

Criteria

Inclusion Criteria:

• Normal healthy volunteers

• Must be able to swallow tablets

Exclusion Criteria:

• Insulin dependent diabetes

• Thyroid disease

• any medial treatment