Absorption, Distribution, Metabolism and Excretion of BIA 5-1058
Status:
Completed
Trial end date:
2017-05-24
Target enrollment:
Participant gender:
Summary
the purpose of this study is:
- to determine the rate and routes of excretion of BIA 5-1058 and the mass balance in
urine, feces and exhaled air, after a single oral dose of 400 mg 14C labeled BIA 5 1058
containing 3.7 Megabecquerel (MBq) of radiocarbon;
- to determine the pharmacokinetics (PK) of total radioactivity (TRA) in plasma and whole
blood and to assess the blood-to-plasma ratio;
- to determine the PK of BIA 5-1058 and its metabolites in plasma.