Overview

Abraxane and Alimta in Advanced Solid Tumors

Status:
Terminated
Trial end date:
2014-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Pemetrexed may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving paclitaxel albumin-stabilized nanoparticle formulation together with pemetrexed may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of paclitaxel albumin-stabilized nanoparticle formulation when given together with pemetrexed and to see how well they work in treating patients with advanced non-small cell lung cancer, breast cancer, or other solid tumors.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of California, Davis
Collaborators:
Celgene
Celgene Corporation
Eli Lilly and Company
Treatments:
Albumin-Bound Paclitaxel
Paclitaxel
Pemetrexed