Abnormal Uterine Bleeding and Progestin-only Contraceptives
Status:
Completed
Trial end date:
2020-11-01
Target enrollment:
Participant gender:
Summary
The use of progestin-only methods of contraception has been increased obviously and
progressively over the world in the last few years. Progestin-only contraception is an option
for women in whom an estrogen-containing contraceptive is either contraindicated or causes
additional health concerns.
Progestogen-only pills are contraceptive pills that contain only synthetic progestogens
(progestins) and do not contain estrogen . The progestin-only pill is recommended over
regular birth control pills for women who are breastfeeding because the mini-pill does not
affect milk production.
The most common progestin-only method used is the injectable depot medroxy-progesterone
acetate which had been approved by Food and Drug Administration since 1992 . depot
medroxy-progesterone acetate provides reliable, private, long-acting (three months) and
reversible contraception. Users of depot medroxy-progesterone acetate don't need daily taking
as well as it doesn't affect the intercourse by any mean.
The etonogestrel implant (Implanon) is a single-rod progestin contraceptive method placed
subdermally in the inner aspect of upper non dependant arm for three years. Much evidence
supports the safety, efficacy, reversibility and acceptability of this contraceptive method.
A common reason women choose to discontinue progestin-only contraception is dissatisfaction
with its effects on uterine bleeding which occurs in a significant number of users.
Information revealed from many clinical trials shows that abnormal uterine bleeding with
progestin-only contraception ranging from 10 to 25 % at first year of use.