Abiraterone Prednisone and Hormonal Therapy Before and During Radiation Therapy in Localized Prostate Cancer
Status:
Completed
Trial end date:
2015-09-01
Target enrollment:
Participant gender:
Summary
This phase II trial studies the side effects and how well abiraterone acetate, prednisone,
and leuprolide acetate or goserelin before and during radiation therapy works in treating
patients with localized or locally advanced prostate cancer. Androgens can cause the growth
of prostate cancer cells. Antihormone therapy, such as abiraterone acetate, leuprolide
acetate, and goserelin, may lessen the amount of androgens made by the body. Radiation
therapy uses high-energy x-rays to kill tumor cells. Giving abiraterone acetate and
leuprolide acetate or goserelin before or together with radiation therapy may be an effective
treatment for prostate cancer.