Abbreviated MgSO4 Therapy in Post-Partum Preeclampsia
Status:
Completed
Trial end date:
2004-08-01
Target enrollment:
Participant gender:
Summary
Magnesium sulfate is used for seizure prophylaxis in pregnancies complicated by preeclampsia.
There is debate as to how long to continue this therapy after delivery of the pregnancy.
Different schemes have been offered to shorten the exposure to magnesium sulfate after
delivery, with little data. We seek to investigate the effect of shortened magnesium sulfate
therapy on the post-partum recovery phase of mild preeclampsia. Our hypothesis was that
shortened therapy (12 hours versus the traditional 24 hours post-partum) has no effect on
disease course, and will result in significantly shorter exposure to magnesium sulfate.