Overview

Abaloparatide and Pelvic Fracture Healing

Status:
Recruiting
Trial end date:
2023-12-01
Target enrollment:
Participant gender:
Summary
This is a prospective randomized, double-blinded, placebo-controlled, phase 2, three-month study of the efficacy of abaloparatide in postmenopausal women and men ≥ 50 years of age with acute fractures of the pelvis (n=78). The primary outcome is CT image based evidence of fracture healing. The secondary aims are pain and physical performance measures at 3 months. This study will be extended with 9 months of open label abaloparatide to determine if any potential differences between the placebo and abaloparatide groups during the 3 months of treatment are evident and persist over time, even in patients who use abaloparatide after the three-month placebo controlled intervention.
Phase:
Phase 2
Details
Lead Sponsor:
Hospital for Special Surgery, New York
Collaborators:
Icahn School of Medicine at Mount Sinai
Lenox Hill Hospital
New York Hospital Queens
New York University
Weill Medical College of Cornell University
Treatments:
Abaloparatide
Parathyroid Hormone-Related Protein