ANTEAB: a Study of Early Antibiotherapy in the ICU Management of Acute Exacerbations of COPD
Status:
Completed
Trial end date:
2006-10-01
Target enrollment:
Participant gender:
Summary
Intensive Care Unit (ICU) admission for acute exacerbation of chronic obstructive lung
disease (COLD) is a major cause of morbidity and mortality in such patients. Although
bacterial of mortality in such patients. Although bacterial and or viral infections are
considered as the major precipitating factor, the antibiotic strategy in this setting is
unclear. The absence of overt infection remains controversial, and has not been adequately
studied in patients admitted to the ICU. To assess the benefit ( or lack thereof ) of routine
early systemic antibiotic therapy in patients with COLD admitted to the ICU.
The primary objective of the essay is to evaluate the effectiveness of the precocious
antibiotic therapy on the length of the respiratory symptoms with the admitted patients in
polyvalent medical intensive care of chronic obstructive lung disease ( COLD )