Overview

AMelioration of Angiotensin Converting Enzyme Inhibitor Induced Angioedema Study

Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
This is a multicenter study recruiting patients with angioedema induced by ACEI. Open-label treatment with subcutaneous Icatibant compared to a historic group of 47 patients with ACE inhibitor induced angioedema which the investigators have been previously treated in the investigators centers with current "standard" therapy (250 mg methylprednisolon and 2 mg clemastine). In cases with fast progression of edema after application the study-drug, a second application with icatibant could be necessary. Rescue medication and intervention.
Phase:
Phase 2
Details
Lead Sponsor:
Technische Universität München
Treatments:
Angiotensin-Converting Enzyme Inhibitors
Bradykinin
Bradykinin B2 Receptor Antagonists
Cortisone
Icatibant