Overview

AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Status:
Completed
Trial end date:
2019-11-24
Target enrollment:
Participant gender:
Summary
The CENTAUR trial was a 2:1 (active:placebo) randomized, double-blind, placebo-controlled Phase II trial to evaluate the safety and efficacy of AMX0035 for the treatment of ALS.
Phase:
Phase 2
Details
Lead Sponsor:
Amylyx Pharmaceuticals Inc.
Collaborators:
ALS Association
ALS Finding a Cure
ALS Finding a Cure Foundation
Leandro P. Rizzuto Foundation
Massachusetts General Hospital Neurology Clinical Research Institute
Neurological Clinical Research Institute at Massachusetts General Hospital
Northeast ALS Consortium
Treatments:
4-phenylbutyric acid
Taurochenodeoxycholic Acid
Tauroursodeoxycholic acid