AMG 102, Pemetrexed Disodium, and Cisplatin in Treating Patients With Malignant Pleural Mesothelioma
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
This phase II trial is studying how well giving AMG 102 together with pemetrexed disodium and
cisplatin works in treating patients with malignant pleural mesothelioma. Monoclonal
antibodies, such as AMG 102, can block tumor growth in different ways. Some block the ability
of tumor cells to grow or spread. Others find tumor cells and help kill them or carry
tumor-killing substances to them. Drugs used in chemotherapy, such as pemetrexed disodium and
cisplatin, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. Giving AMG 102 together with pemetrexed disodium and
cisplatin may kill more tumor cells