Overview

ALT-801 DDI Study in Healthy Volunteers

Status:
Not yet recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
This is a Phase 1, open-label, drug-drug interaction (DDI) study of ALT-801 under steady state conditions on concomitantly administered medications in healthy subjects. The study will evaluate the effect of ALT-801 on the pharmacokinetics (PK) of metformin, warfarin, atorvastatin, digoxin, and the combined oral contraceptive (OC) ethinylestradiol/levonorgestrel. The study will be conducted in 3 parts, as described below. Each part will have 2 periods in a fixed sequence, where the first period is without ALT-801 administration and the second is with ALT-801 at steady state.
Phase:
Phase 1
Details
Lead Sponsor:
Altimmune, Inc.
Treatments:
Atorvastatin
Digoxin
Ethinyl Estradiol
Levonorgestrel
Metformin
Warfarin