Overview

ALK Tyrosine Kinase Inhibitors in ALK-rearranged Advanced Squamous Cell Carcinoma

Status:
RECRUITING
Trial end date:
2027-08-08
Target enrollment:
Participant gender:
Summary
This study was to explore the efficacy of ALK-TKI in lung squamous cell carcinoma. Approximately 5% of lung adenocarcinomas have oncogenic fusions of EML-4 and ALK a mutation associated with tumorigenesis and migration.
Phase:
PHASE2
Details
Lead Sponsor:
Hunan Province Tumor Hospital
Treatments:
alectinib
brigatinib
Carboplatin
Crizotinib
Immune Checkpoint Inhibitors
lorlatinib
Paclitaxel
Pemetrexed