The purpose of this study is to determine whether Acetyl L-carnitine can prevent the
development of nerve damage, known as neuropathy, in individuals taking anti-HIV drugs over a
48-week period. In addition the safety and tolerability of Acetyl L-carnitine will be
assessed.
This study compares the use of Acetyl L-carnitine or placebo (a dummy drug) in the prevention
of nerve damage. The current standard of care is to use painkillers to manage the pain, with
little or no effect. The possible beneficial effects of taking Acetyl L-carnitine is to
prevent nerve damage as a result of anti-HIV medication.
The main purposes of the trial are:
- to look at the differences in between those on Acetyl L-carnitine versus those on
placebo
- to look at the effect on state of your nervous system in the two treatment groups by
measuring nerve activity
- to learn more about the safety and tolerance of Acetyl L-carnitine