In this study, we propose oral dosing of GIPET enhanced oral acyline (MER-104) to determine
if this potentially useful compound is safe and effective at suppression of gonadotropins
after oral dosing in man.
Hypothesis: A single dose of Acyline will suppress gonadotropins, and testosterone, estradiol
and dihydrotestosterone (DHT) for 24 hours in man, and the magnitude and duration of the
suppression will increase with increasing doses of Acyline.