Overview

ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19

Status:
Recruiting
Trial end date:
2023-04-01
Target enrollment:
Participant gender:
Summary
This study looks at the safety and effectiveness of different drugs in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure. Participants in the study will be treated with either a study drug plus current standard of care (SOC), or with placebo plus current SOC.
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborators:
AIDS Clinical Trials Group
Cardiothoracic Surgical Trials Network (CTSN)
Gilead Sciences
International Network for Strategic Initiatives in Global HIV Trials (INSIGHT)
Kirby Institute
Medical Research Council
National Heart, Lung, and Blood Institute (NHLBI)
NeuroRx, Inc.
Prevention and Early Treatment of Acute Lung Injury (PETAL)
University of Copenhagen
US Department of Veterans Affairs
Washington D.C. Veterans Affairs Medical Center
Treatments:
Phentolamine
Remdesivir
Vasoactive Intestinal Peptide