Overview

ACT01 in Combination With Comp01-04 in Patients With Actinic Keratosis

Status:
Completed
Trial end date:
2014-09-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to determine whether or not ACT01 is effective and tolerable alone or when used in combination with Comp01, Comp02, Comp03 or Comp04 in patients with facial and/or scalp keratosis.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Promius Pharma, LLC
Criteria
Inclusion Criteria:

1. Presence of actinic keratosis lesions on the face and/or scalp within a 25 cm2
contiguous area containing at least four lesions that are non-hypertrophic and
non-hyperkeratotic and not larger than 6 mm in longest diameter.

2. Age 30-85 years, inclusive.

3. Good general health as determined by investigator and supported by medical history and
normal or not clinically significant abnormal vital signs (blood pressure and pulse).

Exclusion Criteria:

1. Severe, uncontrolled auto-immune, cardiovascular, gastrointestinal, hematological,
hepatic, neurological, pancreatic, pulmonary or renal disease.

2. Dermatologic conditions if present on the face such as acne, atopic dermatitis,
seborrheic dermatitis, eczema, rosacea, or albinism.

3. Application of 1) chemical peel, 2) dermabrasion, 3) laser abrasion, 4) PUVA (psoralen
plus ultraviolet A) therapy, or 5) UVB therapy to the intended treatment area within
180 days prior to the Baseline Visit.

4. Use of sun lamps or sun tanning beds or booths during the 14 days prior to the
Baseline Visit.