Overview

ABL001 + Dasatinib + Prednisone in BCR-ABL+ B-ALL or CML

Status:
Recruiting
Trial end date:
2024-11-01
Target enrollment:
Participant gender:
Summary
This research study is evaluating a drug called ABL001 taken in combination with dasatinib (Sprycel®) and prednisone (a steroid) as a possible treatment for B-cell Acute Lymphoblastic Leukemia that is BCR-ABL positive (BCR-ABL+ B-ALL) or Chronic Myeloid Leukemia (CML) in lymphoid blast crisis. BCR-ABL+ B-ALL is also called Philadelphia chromosome positive Acute Lymphoblastic Leukemia (Ph+ ALL). It is expected that 25-34 people will take part in this research study. - ABL001 - Dasatinib (Sprycel®) - Prednisone
Phase:
Phase 1
Details
Lead Sponsor:
Marlise R. Luskin
Collaborator:
Novartis
Treatments:
Dasatinib
Prednisone