A Two Chemoprophylaxis Approaches After Phacoemulsification Surgery
Status:
Completed
Trial end date:
2018-02-01
Target enrollment:
Participant gender:
Summary
Post cataract surgery bacterial endophthalmitis is a rare but the most devastating
complication with a poor visual outcome.
The preferred pattern of chemoprophylaxis varied world widely. The use of preoperative
povidone iodine is universal. Most European surgeons prefer the use of Intracameral (IC)
antibiotics whereas topical fluoroquinolone that prescribed perioperatively is the most
common pattern in the United state(US). The current study aimed to evaluate the effectivity
and safety of a combination of diluted IC Moxifloxacin and subconjunctival (SC) Triamcinolone
acetonide as prophylaxis of bacterial endophthalmitis and postoperative inflammation in five
hundred phacoemulsification surgeries and compare its results with the same number of
patients treated by topical Moxifloxacin hydrochloride and Dexamethasone eye drops when given
four times a day for 1month postoperatively.