Overview

A Trial of Lenvatinib Plus Pembrolizumab in Participants With Hepatocellular Carcinoma

Status:
Active, not recruiting
Trial end date:
2022-09-30
Target enrollment:
Participant gender:
Summary
This is an open-label Phase 1b study designed to evaluate the tolerability and safety of lenvatinib in combination with pembrolizumab in participants with hepatocellular carcinoma (HCC). The study will evaluate objective response rate and duration of response by modified Response Evaluation Criteria In Solid Tumors (mRECIST) for HCC and Response Evaluation Criteria In Solid Tumors (RECIST 1.1) based on independent imaging review (IIR).
Phase:
Phase 1
Details
Lead Sponsor:
Eisai Co., Ltd.
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Lenvatinib
Pembrolizumab