Overview

A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis

Status:
Completed
Trial end date:
2019-02-01
Target enrollment:
Participant gender:
Summary
We will conduct a randomized placebo controlled trial to determine whether administration of intravenous (IV) NAC to participants with TB DIH, in dosages similar to that used in paracetamol poisoning, can improve recovery from hepatotoxicity.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
University of Cape Town
Collaborator:
Medical Research Council, South Africa
Treatments:
Acetylcysteine
Antitubercular Agents
N-monoacetylcystine