A Trial Assessing Peri-procedure Chemoprophylaxis During Transrectal Prostate Needle Biopsy

• Status: Completed
• Trial end date: 2017-04-01
• Target enrollment: 0
• Participant gender: Male

Summary

The aim of the study is to evaluate whether changing antibiotic prophylaxis from fluoroquinolones alone to fluoroquinolones plus gentamicin 160mg single IM dose or targeted antibiotic prophylaxis according to rectal swab culture would influence infectious complication rates in those men undergoing transrectal ultrasound-guided prostate biopsy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Ciprofloxacin; Gentamicins

Criteria

Inclusion Criteria:

1. Prothrombin concentration > 70%

2. Platelet count > 100.000/cm

Exclusion Criteria:

1. Acute prostatitis (positive symptoms and signs)

2. Patients with compromised renal function (serum creatinine >1.6 mg/dl)

3. Uncontrolled DM

4. Patients on immunosuppressive therapy

5. Active steroid intake

6. Untreated bleeding diathesis